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Experiment grows new muscle in men’s injured legs

Published: Thursday, May 1, 2014 11:20 a.m. CDT

WASHINGTON (AP) — Scientists implanted thin sheets of scaffolding-like material from pigs into a few young men with disabling leg injuries — and say the experimental treatment coaxed the men’s own stem cells to regrow new muscle.

The research, funded by the Defense Department, included just five patients, a small first step in the complex quest for regenerative medicine.

But the researchers described some of the men improving enough to no longer need canes, or to ride a bicycle again, after years of living with injuries that today have no good treatment.

“The real rush for someone like myself is to see this patient being able to do these things and not struggle and have a smile on his face,” said Dr. Stephen Badylak of the University of Pittsburgh School of Medicine. He led the study, which was reported Wednesday in the journal Science Translational Medicine.

The new experiment combines bioengineering with a heavy dose of physical therapy to spur stem cells that are roaming the body to settle on the injury and turn into the right kind of tissue to repair it.

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